：Barley Grass Extract

DESCRIPTION
Cereal grass is the young green plant that grows to produce the cereal grain. Grasses belong to the Gramineae family that provides all the world's cereals and most of the world's sugar. Wheat grass and barley grass are popular nutritional supplements. These cereal grasses, along with spirulina (see Spirulina), chlorella (see Chlorella), oat grass and alfalfa are sometimes referred to as "green foods." Wheat grass and barley grass are rich sources of chlorophyll (see Chlorophyll/Chlorophyllin), which is believed to have some health-promoting activities.

ACTIONS AND PHARMACOLOGY
ACTIONS
Wheat grass and barley grass have putative anticarcinogenic activity.

MECHANISM OF ACTION
Wheat sprout extracts have demonstrated antimutagenic activity in vitro. The mechanism of the antimutagenic effect is unclear. Wheat sprouts and wheat grass are rich in chlorophyll, and the antimutagenic activity of wheat sprouts may be accounted for by the presence of this substance, which is known to have antimutagenic and anticarcinogenic activities (see Chlorophyll/Chlorophyllin). Other substances, including flavonoids, may also play a role in these possible activities. Barley grass extracts have been found to protect human fibroblasts against carcinogenic agents. Again, chlorophyll may, in part, account for this effect. Barley grass contains several substances other than chlorophyll that have antioxidant activity and that may contribute to its possible antimutagenic and anticarcinogenic activities.

PHARMACOKINETICS
The proteins, lipids and carbohydrates in wheat grass and barley grass are digested, absorbed and metabolized by normal physiological processes.

INDICATIONS AND USAGE
Wheat grass/barley grass supplements are promoted for multiple uses. Claims have been made that they help prevent and fight cancer, lower cholesterol, detoxify many pollutants, protect against solar and other forms of radiation, boost energy and immunity, enhance wound healing, help with digestion, fight tooth decay and bad breath, promote healthy skin, reverse graying of hair and lower blood pressure, among other things. There is no credible evidence to support any of these claims at this time.

RESEARCH SUMMARY
Research is lacking on the possible effects of wheat grass and barley grass. Given that they contain chlorophyll, it is possible that they might have some of the activities exhibited by that substance, including antimutagenic and anticarcinogenic activities. See Chlorophyll/Chlorophyllin.

CONTRAINDICATIONS, PRECAUTIONS, ADVERSE REACTIONS
CONTRAINDICATIONS
Wheat grass and barley grass are contraindicated in those who are hypersensitive to any component of a wheat grass- or barley grass-containing supplement.

PRECAUTIONS
Pregnant women and nursing mothers should avoid wheat grass- or barley grass-containing supplements.

Wheat grass supplements may contain high amounts of vitamin K. Those on warfarin should exercise caution in the use of wheat grass supplements.

ADVERSE REACTIONS
No reports of adverse reactions.

INTERACTIONS
Some wheat grass supplements may be rich in vitamin K and may affect the INR of those on warfarin.

DOSAGE AND ADMINISTRATION
There are various forms of wheat grass and barley grass supplements. Both are available as a powder, in tablets and as a juice. It is also available as a juice. Wheat grass and barley grass are also found in combination "green food" products with spirulina, chlorella, oat grass and alfalfa. Those who use wheat grass typically take 3.5 grams daily. The typical dose of barley grass is also about 3.5 grams daily.

HOW SUPPLIED
Barley grass is supplied as follows:

Capsules470 mg, 475 mg, 500 mg

Powder

Tablets350 mg, 500 mg

Wheat grass is supplied as follows:

Capsules500 mg

Powder

Tablets500 mg